Silent Crohn's Disease: Asymptomatic Patients with Elevated C-reactive Protein Are at Risk for Subsequent Hospitalization.

@article{Click2015SilentCD,
  title={Silent Crohn's Disease: Asymptomatic Patients with Elevated C-reactive Protein Are at Risk for Subsequent Hospitalization.},
  author={Benjamin H. Click and Eric J. Vargas and Alyce J M Anderson and Siobhan S Proksell and Ioannis E Koutroubakis and Claudia M Ramos Rivers and Jana Ghazi Hashash and M. Dolores Nu{\'u}{\~n}ez Regueiro and Alexandria R. Watson and Michael A Dunn and Marc B. Schwartz and Jason M. Swoger and Leonard Baidoo and Arthur M. Barrie and David G. Binion},
  journal={Inflammatory bowel diseases},
  year={2015},
  volume={21 10},
  pages={
          2254-61
        }
}
BACKGROUND Patient-reported Crohn's disease (CD) symptoms and endoscopic evaluation have historically guided routine care, but the risk of complications in asymptomatic patients with elevated C-reactive protein (CRP) is unknown. METHODS We conducted a prospective observational cohort study of patients with CD from a tertiary care center. Subjects with short inflammatory bowel disease questionnaire scores ≥ 50, Harvey-Bradshaw CD scores ≤ 4, and same-day CRP measurement were eligible for… CONTINUE READING
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