Silencing urokinase in the ventral tegmental area in vivo induces changes in cocaine-induced hyperlocomotion.

Abstract

Serine proteases in the nervous system have functional roles in neural plasticity. Among them, urokinase-type plasminogen activator (uPA) exerts a variety of functions during development, and is involved in learning and memory. Furthermore, psychostimulants strongly induce uPA expression in the mesolimbic dopaminergic pathway. In this study, doxycycline… (More)

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@article{Bah2006SilencingUI, title={Silencing urokinase in the ventral tegmental area in vivo induces changes in cocaine-induced hyperlocomotion.}, author={Amine Bah{\'i} and Fr{\'e}d{\'e}ric Boyer and Tal Kafri and J. Dreyer}, journal={Journal of neurochemistry}, year={2006}, volume={98 5}, pages={1619-31} }