Silencing of Wnt5a during colon cancer metastasis involves histone modifications.

@article{Li2012SilencingOW,
  title={Silencing of Wnt5a during colon cancer metastasis involves histone modifications.},
  author={Qian Li and Hong Chen},
  journal={Epigenetics},
  year={2012},
  volume={7 6},
  pages={551-8}
}
Colorectal cancer (CRC) is the third most common cancer in the United States. Approximately 90% of colon cancer deaths arise from the metastasis of primary tumors. Aberrant expression of Wnt5a, one of the WNT signaling factors, has been reported during colon cancer development and progression. We found that both mRNA and protein expression of Wnt5a were… CONTINUE READING