Silencing of TRB3 Ameliorates Diabetic Tubule Interstitial Nephropathy via PI3K/AKT Signaling in Rats

Abstract

BACKGROUND Nephropathy, a chronic progressive kidney disease often characterized by glomeruli scarring and sclerosis, is a major complication of diabetes mellitus. Development of nephropathologic lesions has been shown to be associated with suppressed AKT phosphorylation and elevated level of apoptosis. Moreover, it has been established that the TRB3 gene… (More)

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Cite this paper

@inproceedings{Ma2017SilencingOT, title={Silencing of TRB3 Ameliorates Diabetic Tubule Interstitial Nephropathy via PI3K/AKT Signaling in Rats}, author={Yali Ma and Fang Chen and Suxia Yang and Yurui Duan and Zhiqiang Sun and Jun Shi}, booktitle={Medical science monitor : international medical journal of experimental and clinical research}, year={2017} }