Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells.

@article{Liu2016SilencingOM,
  title={Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells.},
  author={Yuan-Fei Liu and Guo-qiang Qu and Yun-Min Lu and W Q Kong and Yuan Liu and Wei-Xiong Chen and Xiao-Hong Liao},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 1},
  pages={41-8}
}
Gastric cancer (GC) is the second most common cause of cancer‑associated mortality worldwide. Previous studies suggest that mitogen‑activated protein kinase kinase kinase kinase isoform 4 (MAP4K4) is involved in cancer cell growth, apoptosis and migration. In the present study, bioinformatics analysis and reverse transcription‑quantitative polymerase chain… CONTINUE READING