Silencing of Long Noncoding RNA AK139328 Attenuates Ischemia/Reperfusion Injury in Mouse Livers

@inproceedings{Chen2013SilencingOL,
  title={Silencing of Long Noncoding RNA AK139328 Attenuates Ischemia/Reperfusion Injury in Mouse Livers},
  author={Zhenzhen Chen and Shi Jia and Danhua Li and Junyan Cai and Jian Tu and Bin Geng and You-fei Guan and Qinghua Cui and Jichun Yang},
  booktitle={PloS one},
  year={2013}
}
Recently, increasing evidences had suggested that long noncoding RNAs (LncRNAs) are involved in a wide range of physiological and pathophysiological processes. Here we determined the LncRNA expression profile using microarray technology in mouse livers after ischemia/reperfusion treatment. Seventy one LncRNAs were upregulated, and 27 LncRNAs were downregulated in ischemia/reperfusion-treated mouse livers. Eleven of the most significantly deregulated LncRNAs were further validated by… CONTINUE READING
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LncRNA-LALR1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/beta-Catenin signaling. Hepatology

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