Silencing-induced metaplasticity in hippocampal cultured neurons.

  title={Silencing-induced metaplasticity in hippocampal cultured neurons.},
  author={Irina V Sokolova and Istv{\'a}n M{\'o}dy},
  journal={Journal of neurophysiology},
  volume={100 2},
Silencing-induced homeostatic plasticity is usually expressed as a change in the amplitude or the frequency of miniature postsynaptic currents. Here we report that, prolonged (approximately 24 h) silencing of mature (20-22 days in vitro) cultured hippocampal neurons using the voltage-gated sodium channel blocker tetrodotoxin (TTX) produced no effects on the amplitude or frequency of the miniature excitatory postsynaptic currents (mEPSCs). However, the silencing changed the intrinsic membrane… CONTINUE READING
10 Citations
38 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 38 references

revealed by intracellular dialysis of murine neurones in culture

  • VN Murthy, T Schikorski, CF Stevens, Y Zhu
  • J Physiol
  • 2001
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…