Silencing D. melanogaster lgr1 impairs transition from larval to pupal stage.

@article{Vandersmissen2014SilencingDM,
  title={Silencing D. melanogaster lgr1 impairs transition from larval to pupal stage.},
  author={Hans Peter Vandersmissen and Matthias B. Van Hiel and Tom Van Loy and Rut K Vleugels and Jozef Vanden Broeck},
  journal={General and comparative endocrinology},
  year={2014},
  volume={209},
  pages={
          135-47
        }
}
G protein-coupled receptors (GPCRs) play key roles in a wide diversity of physiological processes and signalling pathways. The leucine-rich repeats containing GPCRs (LGRs) are a subfamily that is well-conserved throughout most metazoan phyla and have important regulatory roles in vertebrates. Here, we report on the critical role of Drosophila melanogaster LGR1, the fruit fly homologue of the vertebrate glycoprotein hormone receptors, in development as a factor involved in the regulation of… CONTINUE READING
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