Silence of the ROS.


Reactive oxygen species (ROS) are generated during T cell activation and serve a signaling function but can also be damaging. In this issue of Immunity, Zhang et al. (2016) show that miR-23a prevents ROS-elicited necrosis by suppressing cyclophilin D (PPIF), a regulator of ROS escape from mitochondria. 
DOI: 10.1016/j.immuni.2016.02.027


1 Figure or Table

Cite this paper

@article{Agudo2016SilenceOT, title={Silence of the ROS.}, author={Judith Agudo and Brian D. Brown}, journal={Immunity}, year={2016}, volume={44 3}, pages={520-522} }