Silence of long noncoding RNA UCA1 inhibits malignant proliferation and chemotherapy resistance to adriamycin in gastric cancer

@article{Shang2016SilenceOL,
  title={Silence of long noncoding RNA UCA1 inhibits malignant proliferation and chemotherapy resistance to adriamycin in gastric cancer},
  author={C. G. Shang and Yan Guo and Jiaxing Zhang and Baojun Huang},
  journal={Cancer Chemotherapy and Pharmacology},
  year={2016},
  volume={77},
  pages={1061-1067}
}
Urothelial carcinoma associated 1 (UCA1) gene is a long noncoding RNA (lncRNA), which shows expression and function abnormality in some kinds of malignant cancers. This study aimed to investigate its clinical significance and to examine its regulative effects of malignant proliferation and chemosensitivity to doxorubicin in gastric cancer cells. The expression of UCA1 was detected by quantitative real-time PCR. Statistical analysis was used to determine the relationship between UCA1 expression… CONTINUE READING
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Long Non-Coding RNA (LncRNA) Urothelial Carcinoma Associated 1 (UCA1) Increases Multi-Drug Resistance of Gastric Cancer via Downregulating miR-27b

Medical science monitor : international medical journal of experimental and clinical research • 2016
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Aberrant expression of UCA1 in gastric cancer and its clinical significance.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico • 2015
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