Sildenafil response is influenced by the G protein beta 3 subunit GNB3 C825T polymorphism: a pilot study.

Abstract

PURPOSE Sildenafil is the oral phosphodiesterase-5 inhibitor that revolutionized treatment for erectile dysfunction. We investigated a potential association of the G protein beta 3 subunit (GNB3) C825T polymorphism, a determinant of intracellular signal transduction, with the drug response to sildenafil in patients with erectile dysfunction. MATERIALS AND… (More)

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Cite this paper

@article{Sperling2003SildenafilRI, title={Sildenafil response is influenced by the G protein beta 3 subunit GNB3 C825T polymorphism: a pilot study.}, author={Herbert V. Sperling and Andreas Eisenhardt and Sebastian Virchow and Ekkehard W. Hauck and Severin V Lenk and Hartmut Porst and Christain Stief and Ulrich Wetterauer and Herbert Rubben and Norbert Muller and Winfried Siffert}, journal={The Journal of urology}, year={2003}, volume={169 3}, pages={1048-51} }