Sildenafil reduces pulmonary vascular resistance in single ventricular physiology.


BACKGROUND High pulmonary vascular resistance (PVR) may be a risk factor for early and late mortality in both Glen shunt and Fontan operation patients. Furthermore, PVR may increase long after the Fontan operation. Whether pulmonary vasodilators such as phosphodiesterase 5 inhibitors can decrease PVR in patients with single ventricular physiology remains… (More)
DOI: 10.1016/j.ijcard.2016.06.322


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