Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.

Abstract

PURPOSE We determined the effect of passive secondhand cigarette smoke on 1) erectile function in vivo, 2) molecular mechanisms involved in penile vascular function, and 3) erectile function and penile molecular signaling in the presence of phosphodiesterase type 5 inhibitor therapy. MATERIALS AND METHODS Four groups of mice were used, including group 1… (More)
DOI: 10.1016/j.juro.2008.10.062

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Cite this paper

@article{Bivalacqua2009SildenafilIS, title={Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.}, author={Trinity J. Bivalacqua and Thomas Sussan and Melina A Gebska and Travis D Strong and Dan E. Berkowitz and Shyam Biswal and Arthur Louis Burnett and Hunter C. Champion}, journal={The Journal of urology}, year={2009}, volume={181 2}, pages={899-906} }