Sildenafil decreased pulmonary arterial pressure but may have exacerbated portal hypertension in a patient with cirrhosis and portopulmonary hypertension

@article{Wang2006SildenafilDP,
  title={Sildenafil decreased pulmonary arterial pressure but may have exacerbated portal hypertension in a patient with cirrhosis and portopulmonary hypertension},
  author={Ying-Wen Wang and H. -T. Lin and Ying-ying Yang and M C Hou and S V Lee},
  journal={Journal of Gastroenterology},
  year={2006},
  volume={41},
  pages={593-597}
}
Portopulmonary hypertension is a recognized but uncommon complication of cirrhosis. Liver transplantation may be contraindicated in patients with severe portopulmonary hypertension. In order to decrease the pulmonary arterial pressure, intravenous administration of epoprostenol has been shown to provide substantial beneficial results in these patients. Additionally, a recent case report demonstrated that long-term oral administration of sildenafil decreased pulmonary arterial pressure, but its… CONTINUE READING
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