Significant weight loss following clozapine use, how is it possible? A case report and review of published cases and literature relevant to the subject.

@article{Tungaraza2016SignificantWL,
  title={Significant weight loss following clozapine use, how is it possible? A case report and review of published cases and literature relevant to the subject.},
  author={Tongeji Elifazi Tungaraza},
  journal={Therapeutic advances in psychopharmacology},
  year={2016},
  volume={6 5},
  pages={335-342}
}
It has been repeatedly shown that clozapine is more efficacious than other antipsychotics in the management of treatment-resistant schizophrenia. However, clozapine is associated with a number of side effects including weight gain. Antipsychotic-induced weight gain has been linked with a number of untoward events including psychological factors such as stigma and low self-esteem, and physical factors such as metabolic syndromes and untimely death. The mechanism underlying antipsychotic… CONTINUE READING
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