Significant role of an exocellular protease in utilization of heme by Vibrio vulnificus.

@article{Nishina1992SignificantRO,
  title={Significant role of an exocellular protease in utilization of heme by Vibrio vulnificus.},
  author={Yuichiro Nishina and Shin-ichi Miyoshi and Akihiro Nagase and Sumio Shinoda},
  journal={Infection and immunity},
  year={1992},
  volume={60 5},
  pages={2128-32}
}
Clinical and environmental isolates of Vibrio vulnificus could grow in a synthetic medium supplemented with heme protein as the iron source. Protease-deficient mutants of the bacterium could not utilize any of the heme proteins in the synthetic medium, but the addition of purified V. vulnificus protease restored their growth. The protease digested all heme… CONTINUE READING