Significant loss of pyramidal neurons in the angular gyrus of patients with Huntington's disease.

@article{Macdonald1997SignificantLO,
  title={Significant loss of pyramidal neurons in the angular gyrus of patients with Huntington's disease.},
  author={Virginia Macdonald and Glenda M Halliday and Ronald J. A. Trent and E. A. McCusker},
  journal={Neuropathology and applied neurobiology},
  year={1997},
  volume={23 6},
  pages={492-5}
}
The primary site of pathology in Huntington's disease (HD) is the caudate nucleus. However, cortical changes are also commonly reported. While many researchers have studied pathology in the frontal lobe, little attention has been paid to posterior cortical regions. The aim of this study is to examine pathology in the parietal lobe in patients with HD as it has specific projections to the caudate nucleus. Post-mortem brain tissue was obtained from HD patients with both a positive family history… CONTINUE READING
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