Significant inter‐ and intra‐laboratory variation in grading of invasive breast cancer: A nationwide study of 33,043 patients in the Netherlands

@article{Dooijeweert2019SignificantIA,
  title={Significant inter‐ and intra‐laboratory variation in grading of invasive breast cancer: A nationwide study of 33,043 patients in the Netherlands},
  author={C. van Dooijeweert and P. V. van Diest and S. Willems and C. Kuijpers and E. van der Wall and L. Overbeek and I. Deckers},
  journal={International Journal of Cancer},
  year={2019},
  volume={146},
  pages={769 - 780}
}
Accurate, consistent and reproducible grading by pathologists is of key‐importance for identification of individual patients with invasive breast cancer (IBC) that will or will not benefit from adjuvant systemic treatment. We studied the laboratory‐specific grading variation using nationwide real‐life data to create insight and awareness in grading variation. Synoptic pathology reports of all IBC resection‐specimens, obtained between 2013 and 2016, were retrieved from the nationwide Dutch… Expand

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