Significant differences in the material properties between aged human and porcine aortic tissues.

  title={Significant differences in the material properties between aged human and porcine aortic tissues.},
  author={Caitlin E Martin and Thuy Minh Pham and Wei Sun},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  volume={40 1},
OBJECTIVE Currently, percutaneous aortic valve (PAV) replacement devices are being investigated to treat aortic stenosis in patients deemed to be of too high a risk for conventional open-chest surgery. Successful PAV deployment and function are heavily reliant on the tissue-stent interaction. Many PAV feasibility trials have been conducted with porcine models under the assumption that these tissues are similar to human; however, this assumption may not be valid. The goal of this study was to… CONTINUE READING

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