Significant changes in the tau A0 and A3 alleles in progressive supranuclear palsy and improved genotyping by silver detection.

@article{Oliva1998SignificantCI,
  title={Significant changes in the tau A0 and A3 alleles in progressive supranuclear palsy and improved genotyping by silver detection.},
  author={Rafael Oliva and Eduardo Tolosa and Mario Ezquerra and Jos{\'e} Luis Molinuevo and Francesc Valldeoriola and J M Burguera and Matilde Calopa and Marzio Villa and Francesca Ballesta},
  journal={Archives of neurology},
  year={1998},
  volume={55 8},
  pages={1122-4}
}
BACKGROUND Progressive supranuclear palsy (PSP) is characterized by intraneuronal inclusions of neurofibrillary tangles formed by aggregated tau protein. A significant association between the tau gene A0/A0 genotype and PSP recently has been reported. OBJECTIVES To determine if a significant association between the tau gene A0/A0 genotype and PSP could be found in an independent population with a genetic background different from that in which the initial association was reported, and to… CONTINUE READING

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