Significant Overexpression of DVL1 in Taiwanese Colorectal Cancer Patients with Liver Metastasis

@inproceedings{Huang2013SignificantOO,
  title={Significant Overexpression of DVL1 in Taiwanese Colorectal Cancer Patients with Liver Metastasis},
  author={Ming-Yii Huang and Li-Chen Yen and Hsueh-Chiao Liu and Po-Ping Liu and Fu-Yen Chung and Tsunai Wang and Jaw-Yuan Wang and Shiu-Ru Lin},
  booktitle={International journal of molecular sciences},
  year={2013}
}
Undetected micrometastasis plays a key role in the metastasis of cancer in colorectal cancer (CRC) patients. The aim of this study is to identify a biomarker of CRC patients with liver metastasis through the detection of circulating tumor cells (CTCs). Microarray and bioinformatics analysis of 10 CRC cancer tissue specimens compared with normal adjacent tissues revealed that 31 genes were up-regulated (gene expression ratio of cancer tissue to paired normal tissue > 2) in the cancer patients… CONTINUE READING

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