Significance of transporter associated with antigen processing gene polymorphism in living related renal transplantation.

@article{Kobayashi2000SignificanceOT,
  title={Significance of transporter associated with antigen processing gene polymorphism in living related renal transplantation.},
  author={Tomoko Kobayashi and Itsuo Yokoyama and Hidetoshi Inoko and Taeko Naruse and Shigeoki Hayashi and Kunio Morozumi and Kazuharu Uchida and Akimasa Nakao},
  journal={Human immunology},
  year={2000},
  volume={61 7},
  pages={670-4}
}
The HLA class I and class II mediated antigen presentation plays a major role in the initiation of immune response and the development of acute rejection after transplantation. The purpose of this study was to examine whether MHC-encoded antigen processing (TAP1, TAP2, LMP2, DMA and DMB) gene polymorphisms were associated with the incidence and the severity of acute rejection after renal transplantation. We studied a selected population of 112 pairs of donors and recipients who underwent living… CONTINUE READING