Significance of signet-ring cells in patients with colorectal cancer.

  title={Significance of signet-ring cells in patients with colorectal cancer.},
  author={Rashmi Pande and Annette Y Sunga and Charles LeVea and Gregory Wilding and Wiam Bshara and Mary Reid and Marwan G. Fakih},
  journal={Diseases of the colon and rectum},
  volume={51 1},
PURPOSE We performed a retrospective study to determine the pattern of metastases and overall outcome of patients with tumors exhibiting a component of signet-ring cells comprising < 50 percent of the tumor mass. METHODS Medical records of 753 patients with primary colorectal cancer were retrospectively studied. Patients who had tumors with < 50 percent signet-ring cells were classified as having a component of signet-ring cells. The outcome of patients with a component of signet-ring cells… CONTINUE READING