Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia.

@article{Sculier1984SignificanceOS,
  title={Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia.},
  author={J. P. Sculier and Jean A. Klastersky},
  journal={The American journal of medicine},
  year={1984},
  volume={76 3},
  pages={429-35}
}
Serum bactericidal activity was determined routinely in 89 patients with gram-negative bacillary bacteremia, 79 of whom were analyzed because they had granulocyte counts either below 100/mm3 or above 1,000/mm3. A peak (one hour after the administration of the antibiotics) serum bactericidal titer of 1:8 or more in non-granulocytopenic patients or 1:16 or more in severely granulocytopenic patients could be correlated with a favorable clinical response, in 98 percent (44 of 45) (p less than 0… CONTINUE READING

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