Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy.

  title={Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy.},
  author={Seitarou Omoto and Shosaku Nomura and Akira Shouzu and Takashi Hayakawa and Hiroaki Shimizu and Yasuhiro Miyake and Takahiro Yonemoto and Mitsushige Nishikawa and Shirou Fukuhara and Mae Inada},
  volume={81 3},
We measured levels of platelet-derived microparticles (PMP), which have coagulative activity and are produced by platelet activation or physical stimulation, and CD62P/CD63-positive platelets in patients with diabetes mellitus to determine their clinical significance and effects on complications of diabetes including diabetic nephropathy. We also compared these levels before and after administration of the antiplatelet drug cilostazol. Plasma PMP and CD62P/CD63-positive platelet levels were… CONTINUE READING


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