Significance of placental damage in vertical transmission of human immunodeficiency virus.

@article{Burton1996SignificanceOP,
  title={Significance of placental damage in vertical transmission of human immunodeficiency virus.},
  author={Graham J Burton and Siobhan O'shea and Tim Rostron and Jane E Mullen and Sujata Aiyer and Jeremy N. Skepper and R. Geoffrey B. Smith and Jangu E Banatvala},
  journal={Journal of medical virology},
  year={1996},
  volume={50 3},
  pages={237-43}
}
The significance of physical breaches of the trophoblastic layer of the placenta in transmission of HIV from mother to infant was evaluated in 17 HIV-infected pregnant women. Samples of peripheral blood were obtained from the women during pregnancy and at delivery, at which time a small piece of placental tissue was obtained from a random site and immediately placed into fixative. Blood samples were obtained from infants at or shortly after birth and thereafter at approximately 3-month… CONTINUE READING