Significance of para-esophageal lymph nodes in food or aeroallergen-induced iNKT cell-mediated experimental eosinophilic esophagitis.

@article{Rajavelu2012SignificanceOP,
  title={Significance of para-esophageal lymph nodes in food or aeroallergen-induced iNKT cell-mediated experimental eosinophilic esophagitis.},
  author={Priya Rajavelu and Madhavi Rayapudi and Matthew G Moffitt and Akanksha Mishra and Anil Mishra},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2012},
  volume={302 7},
  pages={G645-54}
}
Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disorder driven by food hypersensitivity; however, the specific foods and mechanisms involved are unclear. In patients with EoE, we have found that hypersensitivities to corn and peanuts are the most common. Accordingly, we sensitized and exposed mice either intranasally or intragastrically with corn or peanut extract or saline. Esophageal eosinophilia, the genes of eosinophil-directed cytokines, and allergen-induced… CONTINUE READING

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