Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum in vivo.

@article{SchirgiDegen1995SignificanceON,
  title={Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum in vivo.},
  author={A. Schirgi-Degen and Eckhard Beubler},
  journal={British journal of pharmacology},
  year={1995},
  volume={114 1},
  pages={
          13-8
        }
}
1. The effects of inhibiting nitric oxide (NO)-synthase on fluid transport, mucosal cyclic GMP and cyclic AMP levels and intraluminal prostaglandin E2 (PGE2)-release were studied in a model of ligated jejunal loops of anaesthetized rats in vivo. Experiments were performed under basal conditions as well as under conditions, when net fluid secretion was induced by Escherichia coli heat stable enterotoxin a (E. coli STa) or PGE2. 2. Intravenous infusion of the NO-synthase inhibitor N omega-nitro-L… CONTINUE READING

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