Significance of metastasis detected by molecular techniques in sentinel nodes of patients with gastrointestinal cancer

@article{Matsuda2004SignificanceOM,
  title={Significance of metastasis detected by molecular techniques in sentinel nodes of patients with gastrointestinal cancer},
  author={Jun-ichi Matsuda and Y. Nojiri A. Kitagawa and Hirofumi Fujii and Makio Mukai and Katsuaki Dan and Tetsuro Kubota and Masahiko Watanabe and Soji Ozawa and Yoshihide Otani and Hirotoshi Hasegawa and Yoshimasa Shimizu and Koichiro Kumai and Atsushi Kubo and Facs Asa Masaki Kitajima},
  journal={Annals of Surgical Oncology},
  year={2004},
  volume={11},
  pages={250S-254S}
}
The clinical significance of micrometastasis in sentinel nodes (SNs) may differ in various organs. In particular, the prognostic value of SN micrometastases detected by reverse transcriptase-polymerase chain reaction (RT-PCR) is still controversial. We investigated the diagnostic and therapeutic significance of nodal molecular metastasis detected, by nested RT-PCR for cytokeratin (CK) 19 mRNA in gastrointestinal cancer. In 51 cases with GI tract cancer treated by standard curative resection… CONTINUE READING
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