Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture

@article{Kakar2003SignificanceOI,
  title={Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture},
  author={Sanjay Kakar and Vandana Nehra and J A Murray and Gerald A Dayharsh and Lawrence J. Burgart},
  journal={American Journal of Gastroenterology},
  year={2003},
  volume={98},
  pages={2027-2033}
}
OBJECTIVES:The aim of this study was to determine the specificity of increase in intraepithelial lymphocytes (IELs) with normal villous architecture in small bowel biopsy samples for diagnosis of gluten sensitivity (GS) and its significance in the absence of GS.METHODS:Small bowel biopsy samples from 43 patients with increased IELs and no other pathology were reviewed. Patients with prior diagnosis of GS were excluded. A group of 46 patients with normal duodenal biopsy during the same period… CONTINUE READING