Significance of hepatic preneoplasia in risk identification and early detection of neoplasia.

@article{Bannasch2003SignificanceOH,
  title={Significance of hepatic preneoplasia in risk identification and early detection of neoplasia.},
  author={Peter Bannasch and Thomas Haertel and Qin Su},
  journal={Toxicologic pathology},
  year={2003},
  volume={31 1},
  pages={134-9}
}
Among the different types of liver tumor, hepatocellular neoplasms predominate by far in both animals and man. Consequently, preneoplastic foci of altered hepatocytes (FAH), preceding both hepatocellular adenomas and carcinomas, represent the most prevalent form of hepatic preneoplasia observed in animals for a long time, and identified in human chronic liver diseases associated with, or predisposing to, hepatocellular carcinomas more recently. Morphological, microbiochemical, and molecular… CONTINUE READING