Significance of endothelial molecular markers in the evaluation of the severity of acute pancreatitis

@article{Ida2008SignificanceOE,
  title={Significance of endothelial molecular markers in the evaluation of the severity of acute pancreatitis},
  author={Satoshi Ida and Yoshinori Fujimura and Masahiko Hirota and Y U Imamura and Nobuyuki Ozaki and Koichi Suyama and Daisuke Hashimoto and Masaki Ohmuraya and Hiroshi Tanaka and Hiroshi Takamori and Hideo Baba},
  journal={Surgery Today},
  year={2008},
  volume={39},
  pages={314-319}
}
In acute pancreatitis, neutrophil elastase is secreted which damages the endothelial cells. This study was designed to demonstrate that the plasma levels of soluble E-selectin (sES) and soluble thrombomodulin (sTM) serve as endothelial molecular markers; the former is used as an endothelial activation marker, while the latter, as an endothelial injury marker. A total of 27 acute pancreatitis patients were enrolled. The plasma sES and sTM levels were assessed for 10 days after admission. The… CONTINUE READING
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