Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma.

@article{Inoue2014SignificanceOD,
  title={Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma.},
  author={Masafumi Inoue and Yoshihisa Takahashi and Takeshi Fujii and Masanobu Kitagawa and Toshio Fukusato},
  journal={World journal of gastroenterology},
  year={2014},
  volume={20 46},
  pages={17541-51}
}
AIM To investigate the significance of downregulation of liver fatty acid-binding protein (L-FABP) expression in hepatocellular carcinoma (HCC). METHODS Tissue microarrays of 146 cases of HCC were used to perform immunohistochemical staining for L-FABP. For each L-FABP-negative HCC, further immunohistochemical staining was performed using a representative whole-tissue section to confirm the downregulation of L-FABP expression and to assess the intratumoral heterogeneity of the staining… CONTINUE READING