Significance of axillary lymph node metastasis in primary breast cancer.

  title={Significance of axillary lymph node metastasis in primary breast cancer.},
  author={Ismail Jatoi and Susan G. Hilsenbeck and G. M. G. Clark and Charles Osborne},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={17 8},
PURPOSE Axillary lymph node status is the single most important prognostic variable in the management of patients with primary breast cancer. Yet, it is not known whether metastasis to the axillary nodes is simply a time-dependent variable or also a marker for a more aggressive tumor phenotype. The purpose of this study was to determine whether nodal status at initial diagnosis predicts outcome after relapse and therefore also serves as a marker of breast cancer phenotype. PATIENTS AND… CONTINUE READING


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