Significance of asymmetric dimethylarginine (ADMA) concentrations during coronary circulation in patients with vasospastic angina.

@article{Hori2003SignificanceOA,
  title={Significance of asymmetric dimethylarginine (ADMA) concentrations during coronary circulation in patients with vasospastic angina.},
  author={Tomoyuki Hori and Taku Matsubara and Takaharu Ishibashi and Kazuyuki Ozaki and Keiichi Tsuchida and Tohru Mezaki and Takayuki Tanaka and Akimitsu Nasuno and Kaname Kubota and Yuichi Nakamura and Masaru Yamazoe and Yoshifusa Aizawa and Matomo Nishio},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2003},
  volume={67 4},
  pages={305-11}
}
The basal activity of nitric oxide (NO) is reduced in spastic arteries of patients with vasospastic angina (VSA). Elevated concentrations of ADMA are associated with reduced NO production and impaired endothelium-dependent vasodilatation. The aim of this study was to elucidate the role of ADMA and its relationship to NO end-products (NOx; nitrate + nitrite) during coronary circulation in patients with VSA. The plasma ADMA and NOx concentrations during coronary circulation were evaluated in 16… CONTINUE READING

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