Significance of anti-deoxyribonuclease-B (ADN-B) determination in clinical practice.

  title={Significance of anti-deoxyribonuclease-B (ADN-B) determination in clinical practice.},
  author={Satoshi Fujikawa and Seiichi Kawakita and Nozomu Kosakai and Tetsuro Oda and Masahiko Ohkuni and Yuichi Shiokawa and Nozomi Watanabe and Takaaki Yamada},
  journal={Japanese circulation journal},
  volume={46 11},
The determination of anti-deoxyribonuclease-B (ADN-B) is very important for the diagnosis of antecedent streptococcal infection because almost all of group A streptococci have this antigen and a strong elevation of the antibody is observed in patients with acute rheumatic fever, acute glomerulonephritis and other streptococcal infections. Moreover, ADN-B titers are elevated in cases with streptococcal skin infection, whereas anti-streptolysin O (ASO) titers are rarely elevated in these cases… CONTINUE READING

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