Significance of Migrainous Features in Cluster Headache: Divalproex Responsiveness

@article{Wheeler1998SignificanceOM,
  title={Significance of Migrainous Features in Cluster Headache: Divalproex Responsiveness},
  author={Steve D. Wheeler},
  journal={Headache: The Journal of Head and Face Pain},
  year={1998},
  volume={38}
}
  • S. D. Wheeler
  • Published 1 July 1998
  • Medicine
  • Headache: The Journal of Head and Face Pain
Two patients with cluster headache and prominent migrainous features are described and a shared migraine and cluster headache pathophysiology is discussed. Both patients failed routine cluster headache pharmacotherapy, one failed multiple operative interventions; however, both remitted on divalproex. It is suggested that migrainous features be assessed in cluster headache and divalproex initiated before pursuing invasive procedures. 
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24 Citations
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24 Citations

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Citation Type

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The importance of premonitory symptoms is emphasized, for they provide a means to institute an early prophylactic therapy and the possibility of clarifying the physiopathology of this primary headache.
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Evaluation of the effectiveness of topiramate in a group of patients with refractory episodic or chronic cluster headache found it to be effective in both the prevention and treatment of cluster headache.
Update on therapies for cluster headache
  • T. Rozen
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    Expert review of neurotherapeutics
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Cluster headache is one of the primary headache disorders. It is considered the most severe headache syndrome known to humans. In most instances, this disorder is readily treatable when the correct…
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    Current neurology and neuroscience reports
  • 2002
Cluster headache is the most severe headache syndrome known to humans. In most instances, this disorder is readily treatable when the correct medications are utilized at the correct dosages. Cluster…
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The features and treatment ofPrimary headache disorders include migraine, tension-type headaches, and the trigeminal autonomic cephalgias, and hemicrania continua, although classified separately by the International Headache Society, shares many features of both migraine and the TACs.
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  • 2003
TLDR
A case with migraine and cluster-like features such as cranial autonomic symptoms and strict unilaterality is presented.
Cranial Autonomic Features in Migraine and Migrainous Features in Cluster Headache.
TLDR
The assessment of autonomic symptoms is essential, and specialists must consider such an overlap in clinical practice in order to obtain accurate prevalence rates.
Premonitory symptoms in cluster headache
  • E. Raimondi
  • Medicine
    Current pain and headache reports
  • 2001
TLDR
The author believes that premonitory symptoms have not been properly diagnosed and emphasizes the need to investigate their presence, because by knowing them advances can be made in the understanding of the physiopathology of this particular cephalalgia.
Treatment and management of cluster headache
TLDR
The medical treatment of cluster headache includes both acute treatment aimed at aborting individual attacks and prophylactic therapy aimed at preventing recurrent attacks during the cluster period.
Evidence-based treatments for cluster headache
TLDR
Surgical procedures for the chronic refractory form of the disorder should be contemplated, the most promising of which is hypothalamic deep brain stimulation.
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