Significance of Carbohydrate Antigen Sialyl-Lewis X, Sialyl-Lewis A, and Possible Unknown Ligands to Adhesion of Human Urothelial Cancer Cells to Activated Endothelium

@article{Fujii2000SignificanceOC,
  title={Significance of Carbohydrate Antigen Sialyl-Lewis X, Sialyl-Lewis A, and Possible Unknown Ligands to Adhesion of Human Urothelial Cancer Cells to Activated Endothelium},
  author={Yasuhisa Fujii and Masayuki Yoshida and L J Chien and Kazunori Kihara and Yukio Kageyama and Yukio Yasukochi and Hiroyuki Oshima},
  journal={Urologia Internationalis},
  year={2000},
  volume={64},
  pages={129 - 133}
}
Objective: To assess the contribution of the carbohydrate antigens, sialyl-Lewis X (sLex) and sialyl-Lewis A (sLea), which are known to be ligands for E-selectin, to the adhesion between human urothelial cancer cells and cytokine-activated human endothelial cells. Materials and Methods: We studied the expression of sLex and sLea antigens of three bladder cancer cell lines (JTC 30, JTC 32, and T24) by flow cytometry and the adherence to interleukin 1β-activated human umbilical vein endothelial… 
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