Significance of CSF total neopterin and biopterin in inflammatory neurological diseases.

@article{Furukawa1992SignificanceOC,
  title={Significance of CSF total neopterin and biopterin in inflammatory neurological diseases.},
  author={Yasuyuki Furukawa and Katsuo Nishi and Tomoyoshi Kondo and Kazunari Tanabe and Yoshikuni Mizuno},
  journal={Journal of the neurological sciences},
  year={1992},
  volume={111 1},
  pages={65-72}
}
Total neopterin (T-N), a by-product in the biopterin biosynthesis and an indicator of activation of the cellular immune system, and total biopterin (T-B) levels in cerebrospinal fluid (CSF), were measured in patients with various inflammatory neurological diseases and Parkinson's disease, and the following results were obtained. (1) In patients with neuro-sarcoidosis, neuro-Behçet's disease and meningitis, CSF T-N levels were markedly elevated in the exacerbation or acute stages of their… CONTINUE READING
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