Significance of CDKN2A gene A148T variant in patients with bladder cancer

OBJECTIVES The A148T polymorphism of CDKN2A gene is observed in various neoplasms with the incidence rate of 3-35%, however, rather little is known either about the frequency of its occurrence or of its significance in urinary bladder carcinoma. MATERIALS AND METHODS DNA was isolated from blood of 156 patients with urinary bladder carcinoma (130 men). In… CONTINUE READING