Significance of C4d Banff scores in early protocol biopsies of kidney transplant recipients with preformed donor-specific antibodies (DSA).

@article{Loupy2011SignificanceOC,
  title={Significance of C4d Banff scores in early protocol biopsies of kidney transplant recipients with preformed donor-specific antibodies (DSA).},
  author={Alexandre Loupy and Gary S. Hill and Caroline Suberbielle and Dominique J. Charron and Dany Anglicheau and Julien Zuber and Martine Timsit and Jean Duong and Patrick Bruneval and D{\'e}wi Vernerey and Jean Philippe Empana and Xavier P Jouven and Dominique Nochy and Christophe Legendre},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2011},
  volume={11 1},
  pages={
          56-65
        }
}
The significance of C4d-Banff scores in protocol biopsies of kidney transplant recipients with preformed donor-specific antibodies (DSA) has not been determined. We reviewed 157 protocol biopsies from 80 DSA+ patients obtained at 3 months and 1 year post-transplant. The C4d Banff scores (1,2,3) were associated with significant increments of microcirculation inflammation (MI) at both 3 months and 1 year post-transplant, worse transplant glomerulopathy and higher class II DSA-MFI (p < 0.01… CONTINUE READING
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