Significance, specificity, and ultrastructural localization of HMB-45 antigen in pigmented ocular tumors.

@article{Steuhl1993SignificanceSA,
  title={Significance, specificity, and ultrastructural localization of HMB-45 antigen in pigmented ocular tumors.},
  author={Klaus Peter Steuhl and Jens Martin Rohrbach and Marcelo Knorr and H. J. Thiel},
  journal={Ophthalmology},
  year={1993},
  volume={100 2},
  pages={208-15}
}
PURPOSE To evaluate the expression of the monoclonal HMB-45 antibody in melanocytic and nonmelanocytic ocular tumors and seek "activated" cellular subpopulations in an attempt to distinguish between benign and malignant melanocytes, to compare HMB-45 and S100 activity, and to determine the specificity of this tumor marker for melanocytic ocular lesions. METHODS Immunohistologic investigations were performed with paraffin-embedded tissue of 10 acquired conjunctival melanoses, 19 conjunctival… CONTINUE READING
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