Significance, detection and markers of disseminated breast cancer cells.

@article{Lacroix2006SignificanceDA,
  title={Significance, detection and markers of disseminated breast cancer cells.},
  author={Marc Lacroix},
  journal={Endocrine-related cancer},
  year={2006},
  volume={13 4},
  pages={
          1033-67
        }
}
The development of distant metastases is the major cause of death from breast cancer. In order to predict and prevent tumour spreading, many attempts are being made to detect small numbers of tumour cells that have shed from the primary lesions and have moved to lymph nodes, blood or bone marrow. This article presents the advantages and the limitations of techniques used for disseminated tumour cells (DTC) detection. DTC markers are listed and the most currently used of them (KRT19, CEACAM5… CONTINUE READING

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