Signet-ring cell variant of small lymphocytic lymphoma with a prominent sinusoidal pattern.

@article{Ramnani1999SignetringCV,
  title={Signet-ring cell variant of small lymphocytic lymphoma with a prominent sinusoidal pattern.},
  author={Dharamdas M. Ramnani and Gunnar Lindberg and S T Gokaslan and J Albores-saavedra},
  journal={Annals of diagnostic pathology},
  year={1999},
  volume={3 4},
  pages={
          220-6
        }
}
Signet-ring cell lymphoma is a rare morphologic variant of non-Hodgkin's lymphoma characterized by neoplastic lymphoid cells with cytoplasmic vacuoles or eosinophilic globules that impart a signet-ring cell morphology. Although most cases are variants of follicular center B-cell lymphomas, this pattern also can be seen in T-cell lymphomas. An indolent clinical course and prolonged survival have characterized the majority of published cases. We document the case of a 62-year-old African-American… CONTINUE READING
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