Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms.

@article{Lao2007SignaturesOP,
  title={Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms.},
  author={Oscar Lao and Johanna M de Gruijter and Kate van Duijn and Arcadi Navarro and Manfred Kayser},
  journal={Annals of human genetics},
  year={2007},
  volume={71 Pt 3},
  pages={
          354-69
        }
}
  • Oscar Lao, Johanna M de Gruijter, +2 authors Manfred Kayser
  • Published 2007
  • Medicine, Biology
  • Annals of human genetics
  • Phenotypic variation between human populations in skin pigmentation correlates with latitude at the continental level. A large number of hypotheses involving genetic adaptation have been proposed to explain human variation in skin colour, but only limited genetic evidence for positive selection has been presented. To shed light on the evolutionary genetic history of human variation in skin colour we inspected 118 genes associated with skin pigmentation in the Perlegen dataset, studying single… CONTINUE READING

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