Signatures of adaptive molecular evolution in American pikas (Ochotona princeps)

  title={Signatures of adaptive molecular evolution in American pikas (Ochotona princeps)},
  author={Andrew Rankin and Kurt Egan Galbreath and Katherine Carter Teeter},
  journal={Journal of Mammalogy},
  pages={1156 - 1167}
The American pika (Ochotona princeps) is a small, winter-active mammal inhabiting alpine environments. For alpine mammals, metabolic heat production and cellular mechanisms to cope with hypoxia are critical for survival and reproduction. Thus, because of the pikas’ long association with alpine environments, they may have genetically adapted to alpine conditions. Here, we present evidence for positive selection acting at 2 loci within the Ochotona genome. These loci were identified by first… CONTINUE READING
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