Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome.

@article{Morena2013SignatureME,
  title={Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome.},
  author={M Teresa de la Morena and Jennifer L. Eitson and Igor Dozmorov and Serkan Belkaya and Ashley R. Hoover and Esperanza Anguiano and M Virginia Pascual and Nicolai S. C. van Oers},
  journal={Clinical immunology},
  year={2013},
  volume={147 1},
  pages={11-22}
}
Patients with 22q11.2 deletion syndrome have heterogeneous clinical presentations including immunodeficiency, cardiac anomalies, and hypocalcemia. The syndrome arises from hemizygous deletions of up to 3Mb on chromosome 22q11.2, a region that contains 60 genes and 4 microRNAs. MicroRNAs are important post-transcriptional regulators of gene expression, with mutations in several microRNAs causal to specific human diseases. We characterized the microRNA expression patterns in the peripheral blood… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
20 Citations
54 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

H

  • S. C. Saitta, J. M. McGrath
  • Mensch, T.H. Shaikh, E.H. Zackai, B.S. Emanuel, A…
  • 1999
Highly Influential
4 Excerpts

M

  • A. Rauch, R. A. Pfeiffer, G. Leipold, H. Singer, M. Tigges
  • Hofbeck, A novel 22q11.2 microdeletion in…
  • 1999
Highly Influential
4 Excerpts

DIANA miRPath v

  • I. S. Vlachos, N. Kostoulas, +7 authors A. G. Hatzigeorgiou
  • 2.0: investigating the combinatorial effect of…
  • 2012
2 Excerpts

Germline deletion of the miR-17[sim]92 cluster causes skeletal and growth defects in humans

  • L. de Pontual, E. Yao, +15 authors J. Amiel
  • Nat. Genet
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…