Signals leading to the activation of NF-kappa B transcription factor are stronger in neonatal than adult T lymphocytes.

@article{Kilpinen1996SignalsLT,
  title={Signals leading to the activation of NF-kappa B transcription factor are stronger in neonatal than adult T lymphocytes.},
  author={Sanna Kilpinen and Tiina Henttinen and Nina Lahdenpohja and Janne Hulkkonen and Mikko A. Hurme},
  journal={Scandinavian journal of immunology},
  year={1996},
  volume={44 1},
  pages={
          85-8
        }
}
The molecular background of the defects in the immune reactivity of human neonates has not been fully elucidated. As the NF-kappa B transcription factor has a central role in the control of transcription of several genes involved in immune and inflammatory responses, the authors have analysed the activation of NF-kappa B in human umbilical cord T lymphocytes. The activity was tested by quantitating the nuclear proteins binding to an oligonucleotide containing the consensus kappa B binding… CONTINUE READING
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