Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region

@article{Jacks1988SignalsFR,
  title={Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region},
  author={Tyler Jacks and Hiten D. Madhani and Frank R. Masiarz and Harold Varmus},
  journal={Cell},
  year={1988},
  volume={55},
  pages={447 - 458}
}
Abstract The gag-pol protein of Rous sarcoma virus (RSV), the precursor to the enzymes responsible for reverse transcription and integration, is expressed from two genes that lie in different translational reading frames by ribosomal frameshifting. Here, we localize the site of frameshifting and show that the frameshifting reaction is mediated by slippage of two adjacent tRNAs by a single nucleotide in the 5′ direction. The gag terminator, which immediately follows the frameshift site, is… Expand
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  • The Journal of general virology
  • 1995
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Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon.
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