Signalling pathways involved in the cooperative effects of ovine and murine GDF9+BMP15-stimulated thymidine uptake by rat granulosa cells.

@article{Reader2011SignallingPI,
  title={Signalling pathways involved in the cooperative effects of ovine and murine GDF9+BMP15-stimulated thymidine uptake by rat granulosa cells.},
  author={Karen Lee Reader and Derek A Heath and Stan Lun and Carrie McIntosh and Andrea H Western and Roger P. Littlejohn and Kenneth P. McNatty and Jennifer L. Juengel},
  journal={Reproduction},
  year={2011},
  volume={142 1},
  pages={
          123-31
        }
}
Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are oocyte-secreted factors known to be involved in regulating the proliferation and differentiation of granulosa cells during follicular growth. The aims of this study were to determine the signalling pathways used by recombinant forms of murine and ovine GDF9 and BMP15 in combination (GDF9+BMP15) and the molecular complexes formed by combinations of these factors. Differences in the molecular forms of… CONTINUE READING
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